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U.S. Department of Energy Launches Pilot Program to Boost Nuclear Fuel Production

Marc Brousseau by Marc Brousseau
July 17, 2025
in Technology ☆ Science
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The James V. Forrestal Building, home of the Department of Energy, in Washington, D.C. © Genevieve Cocco / Sipa Press / Newscom

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The U.S. Department of Energy (DOE) has announced a new pilot program designed to accelerate the development of advanced nuclear reactors while strengthening the domestic supply chain for nuclear fuel. In a new initiative to reduce reliance on foreign sources for enriched uranium and critical materials, the DOE has issued a Request for Application (RFA) encouraging qualified U.S. companies to establish and operate nuclear fuel production lines through the department’s authorization process.

This significant step aims to catalyze private sector investment in America’s nuclear energy renaissance, aligning with President Trump’s executive orders to reform nuclear reactor testing and deploy innovative nuclear technologies for enhanced national security. Energy Secretary Chris Wright highlighted the United States’ potential, stating, “America has the resources and the expertise to lead the world in nuclear energy development, but we need secure domestic supply chains to fuel this rapidly growing energy source.”

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The program, designed to establish a robust domestic nuclear fuel supply chain, marks a significant step in accelerating the testing of advanced reactor designs. Beginning with a pilot launch, the DOE anticipates selecting at least three advanced reactor designs by July 4, 2026, which are expected to achieve criticality. This urgency reflects the United States’ current shortfall in nuclear fuel resources, which the DOE aims to address through the development of new fuel lines using the same authority designed for reactor testing.

Applicants for the program will assume full responsibility for costs related to the construction, operation, and decommissioning of advanced nuclear fuel lines, as well as the procurement of all nuclear material feedstock. Selections will be based on criteria such as technological readiness, established fuel fabrication plans, and financial viability. Although these nuclear fuel lines will primarily serve research and demonstration purposes, obtaining DOE authorization may also unlock substantial private funding and streamline future commercial licensing activities.

Initial applications are due by August 15, 2025, with subsequent submissions accepted on a rolling basis. For those interested in participating, additional information regarding the RFA can be accessed through the FedConnect listing.

As the U.S. positions itself to lead in nuclear energy advancements, the integration of private sector innovation and resources may significantly contribute to a sustainable, domestic nuclear energy future.

Marc Brousseau

Marc Brousseau

Deputy Editor

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